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https://anti-empire.com/the-inventor-of-the-pcr-technique-would-be-the-first-to-say-its-not-fit-for-diagnostic-purposes/

“The first thing to know is that the test is not binary,” he said. “In fact, I don’t think there are any tests for infectious disease that are positive or negative.”

“What they do is they take some kind of a continuum and they arbitrarily say this point is the difference between positive and negative.”